主要研究方向:
(1)城市环境微生物与人类健康;(2)抗生素抗性基因在环境中的来源和组成、丰度和分布、传播和扩散过程及机制;(3)土壤关键生源要素碳、氮转化的功能过程和微生物学机制。研究组成员:课题组组长:苏建强(研究员、国家优秀青年基金获得者)职工:李虎(副研究员)、安新丽(助理研究员)、周艳艳(助理研究员)、李欢琴(研究实习员)
近5年主要主持项目:
1. 国家重点研发计划,“场地抗生素抗性基因筛查及其传播机制研究”,参加,子课题负责人,290万,2020.11-2024.10,在研,主持;
2. 国家自然科学基金重大项目课题,81991535,动物-环境-人耐药菌/基因传播机制,2020/01-2024/12,430万,参加,子课题负责人,150万,2020.1-2024.12,在研,主持;
3. 国家自然科学基金促进海峡两岸科技合作联合基金,“海峡两岸流域尺度典型新兴污染物污染特征和生态效应”,U1805244,226万,2019.01-2022.12,在研,主持;
4. 国家自然科学基金优秀青年科学基金,“环境抗生素抗性”, 31722004,130万,2018.1-2020.12,结题,主持;
5. 国家重点研发计划,课题“农田抗生素污染及抗性基因增殖扩散机制”,2016YFD0800205,2016.01-2020.12,328万,结题,主持;
6. 中国科学院战略性先导科技专项(B类),“土壤-微生物系统功能及其调控”,子课题“氮素转化关键功能微生物对不同氧化还原梯度的响应机理研究”, XDB15020302,2014.6-2018.5,2014拨款45.6万,2015拨款88万,结题,主持
7. 国家自然科学基金委员会,青年基金项目,41907217,污水处理系统中质粒介导的抗生素抗性基因的扩散机制,2020-01至2022-12,27万元,在研,主持;
8. 厦门市水环境安全与水质保障工程技术研究中心,创新基金项目,WES&WQGE201904,基于光敏剂的水体耐药菌和耐药基因控制技术,2019-04至2020-12,15万元,结题,主持;
9. 国家自然科学基金青年科学基金项目,41701280,水稻根系分泌耦合根际氮素转化的微生物机制,2018/01-2020/12,26万元,结题,主持;
10. 中国科学院城市环境与健康重点实验室跨组合作项目,“肠道微生态健康评价及精准调控研究”,40万, 2017.07-2019.06,结题,主持;
11. 厦门市室内空气与健康重点实验室青年创新课题,“室内空气对人体皮肤及呼吸道微生物影响机制”,9万,2018.05-2019.05,结题,主持。
近5年发表主要论文:
1. Zhu, Y. G*#.; Zhao, Y.#; Li, B.; Huang, C. L.; Zhang, S. Y.; Yu, S.; Chen, Y. S.; Zhang, T.; Gillings, M. R.; Su, J. Q.*, Continental-scale pollution of estuaries with antibiotic resistance genes. Nat Microbiol 2017, 2, 16270.
2.Wang, J. Y.; An, X. L.; Huang, F. Y.; Su, J. Q.*, Antibiotic resistome in a landfill leachate treatment plant and effluent-receiving river. Chemosphere 2020, 242, 125207.
3.Su, J. Q.#; An, X. L.#; Li, B.#; Chen, Q. L.; Gillings, M. R.; Chen, H.; Zhang, T.*; Zhu, Y. G.*, Metagenomics of urban sewage identifies an extensively shared antibiotic resistome in China. Microbiome 2017, 5, (1), 84.
4.Shu-Yi-Dan Zhou?, Hu Li1*?, Madeline Giles, Roy Neilson, Xiao-ru Yang, Jian-qiang Su. Microbial Flow Within an Air-Phyllosphere-Soil Continuum. Frontiers in Microbiology, 2021, 11:615481.
5.Pu, Q.; Zhao, L. X.; Li, Y. T.; Su, J. Q.*, Manure fertilization increase antibiotic resistance in soils from typical greenhouse vegetable production bases, China. J Hazard Mater 2020, 391, 122267.
6.Pu, Q.; Wang, H.-T.; Pan, T.; Li, H.; Su, J.-Q.*, Enhanced removal of ciprofloxacin and reduction of antibiotic resistance genes by earthworm Metaphire vulgaris in soil. Sci Total Environ 2020, 742, 140409.
7.Pu, Q.; Fan, X.-T.; Li, H.; An, X.-L.; Lassen, S. B.; Su, J.-Q.*, Cadmium enhances conjugative plasmid transfer to a fresh water microbial community. Environ Pollut 2021, 268, 115903.
8.Ouyang, W.-Y.; Su, J.-Q.*; Richnow, H. H.; Adrian, L., Identification of dominant sulfamethoxazole-degraders in pig farm-impacted soil by DNA and protein stable isotope probing. Environ Int 2019, 126, 118-126.
9.Liu, L#.; Su, J.-Q.#; Guo, Y.; Wilkinson, D. M.; Liu, Z.; Zhu, Y.-G.; Yang, J.*, Large-scale biogeographical patterns of bacterial antibiotic resistome in the waterbodies of China. Environ Int 2018, 117, 292-299.
10.Li, H.; Zhou, X.-Y.; Yang, X.-R.; Zhu, Y.-G.; Hong, Y.-W.; Su, J.-Q.*, Spatial and seasonal variation of the airborne microbiome in a rapidly developing city of China. Sci Total Environ 2019, 665, 61-68.
11.Hu Li1, Zhi-Feng Wu1, Xiao-Ru Yang, Xin-Li An, Yin Ren*, Jian-Qiang Su*. Urban greenness and plant species are key factors in shaping air microbiomes and reducing airborne pathogens. Environ Int, 2021, 153: 106539.
12.Hu Li, Jian-Qiang Su*, Xiao-Ru Yang, Guo-Wei Zhou, Simon Bo Lassen, Yong-Guan Zhu. RNA stable isotope probing of potential feammox population in paddy soil. Environmental Science and Technology, 2019, 53, 4841-4849.
13.Hu Li, Jian-Qian Su*, Xiao-Ru Yang,Yong-Guan Zhu. Distinct rhizosphere effect on active and total bacterial communities in paddy soils. Science of The Total Environment, 2019, 649: 422-430.
14.Hu Li#, Xiao-Ru Yang#, Bo-Sen Weng, Jian-Qiang Su, San-An Nie, Jack A. Gilbert, Yong-Guan Zhu*. The phenological stage of rice growth determines anaerobic ammonium oxidation activity in rhizosphere soil. Soil Biology and Biochemistry, 2016, 100: 59-65.
15.Fan, X. T.; Li, H.; Chen, Q. L.; Zhang, Y. S.; Ye, J.; Zhu, Y. G.; Su, J. Q.*, Fate of Antibiotic Resistant Pseudomonas putida and Broad Host Range Plasmid in Natural Soil Microcosms. Front Microbiol 2019, 10, (194), 194.
16.Chen, Q.-L.; An, X.-L.; Zheng, B.-X.; Ma, Y.-B.; Su, J.-Q.*, Long-term organic fertilization increased antibiotic resistome in phyllosphere of maize. Sci Total Environ 2018, 645, 1230-1237.
17.Chen, Q.; An, X.; Li, H.; Su, J.; Ma, Y.; Zhu, Y. G.*, Long-term field application of sewage sludge increases the abundance of antibiotic resistance genes in soil. Environ Int 2016, 92-93, 1-10.
18.An, X.-L.; Wang, J.-Y.; Pu, Q.; Li, H.; Pan, T.; Li, H.-Q.; Pan, F.-X.; Su, J.-Q.*, High-throughput diagnosis of human pathogens and fecal contamination in marine recreational water. Environmental research 2020, 109982.
19.An, X.-L.; Chen, Q.-L.; Zhu, D.; Su, J.-Q.*, Distinct effects of struvite and biochar amendment on the class 1 integron antibiotic resistance gene cassettes in phyllosphere and rhizosphere. Sci Total Environ 2018, 631–632, 668-676.
20.An, X.-L.#; Su, J.-Q.#; Li, B.#; Ouyang, W.-Y.; Zhao, Y.; Chen, Q.-L.; Cui, L.; Chen, H.; Gillings, M. R.; Zhang, T.*; Zhu, Y.-G.*, Tracking antibiotic resistome during wastewater treatment using high throughput quantitative PCR. Environ Int 2018, 117, 146-153.
21.An, X. L.; Chen, Q. L.; Zhu, D.; Zhu, Y. G.; Gillings, M. R.; Su, J. Q.*, Impact of Wastewater Treatment on the Prevalence of Integrons and the Genetic Diversity of Integron Gene Cassettes. Appl Environ Microbiol 2018, 84, (9).
22.张毓森; 叶军; 苏建强*, 粪肥与铜一次性施用对农田土壤抗生素抗性基因的长期影响. 应用与环境生物学报 2019, 25, (02), 328-332.